Foundation models are reshaping computational biology. Pretrained on massive corpora of protein or genomic sequences, models such as ESM2 (a protein language...

Foundation models are reshaping computational biology. Pretrained on massive corpora of protein or genomic sequences, models such as ESM2 (a protein language model) and Evo 2 (a DNA language model) capture statistical regularities of biological sequences. These transfer well to a wide range of downstream tasks, including structure prediction, variant effect, and functional annotation.

Source