Biomolecular structure prediction is now often run at proteome scale, where the goal is to move an entire worklist through the pipeline efficiently. NVIDIA...

Biomolecular structure prediction is now often run at proteome scale, where the goal is to move an entire worklist through the pipeline efficiently. NVIDIA BioNeMo Inference Runtime (BioIR) helps accelerate supported biomolecular structure-prediction models on NVIDIA GPUs while keeping the familiar PyTorch workflow. It uses optimized kernels and, where applicable, CUDA Graphs to speed model…

Source

Modern AI platforms are no longer a single application behind one login screen. A user may start in a central portal, open a governed dataset, launch a notebook...

Modern AI platforms are no longer a single application behind one login screen. A user may start in a central portal, open a governed dataset, launch a notebook where that data resides, and invoke an assistant that calls services in another cluster. The workflow feels unified, but identity crosses control-plane and data-plane boundaries at every step. That is where conventional single sign-on…

Source

This post is the third in a series on AI model co-design. It explores how to accelerate LLM inference while maintaining accuracy using speculative decoding and...

This post is the third in a series on AI model co-design. It explores how to accelerate LLM inference while maintaining accuracy using speculative decoding and offers five guidelines for selecting draft length and draft mechanism across the Pareto frontier. For a discussion of how model design choices impact both throughput and interactivity without sacrificing accuracy, see AI Model Co…

Source

The surge in AI adoption is transforming everything from chatbots to content generation. Still, a common pain point remains: How can organizations confidently...

The surge in AI adoption is transforming everything from chatbots to content generation. Still, a common pain point remains: How can organizations confidently size GPU resources for inference workloads and optimize Total Cost of Ownership (TCO)? With a dizzying mix of latency targets, model choices, quirky traffic patterns, and budget constraints, it’s easy to feel lost in the weeds…

Source

Open AI models are evolving faster than ever, but bringing them into native applications can still require model-specific conversion, preprocessing,...

Open AI models are evolving faster than ever, but bringing them into native applications can still require model-specific conversion, preprocessing, post-processing, and runtime code. NVIDIA TensorRT Model Connect open collection of reference implementations helps to address this challenge. TensorRT Model Connect shows you how to run supported models with NVIDIA TensorRT in native C++…

Source

AI factories must support increasingly large models and more complex reasoning workloads. To keep up with the insatiable compute demands of AI workloads,...

AI factories must support increasingly large models and more complex reasoning workloads. To keep up with the insatiable compute demands of AI workloads, hyperscalers and AI-native companies are developing custom AI accelerators, or XPUs. Deploying these accelerators at scale requires high-bandwidth memory (HBM) to keep compute fed, sufficient package and silicon area for more compute…

Source

The massive growth of generative AI has fundamentally altered data center design. As distributed model training scales to span hundreds of thousands of GPUs,...

The massive growth of generative AI has fundamentally altered data center design. As distributed model training scales to span hundreds of thousands of GPUs, the scale-out network connecting these nodes has emerged as a first-order performance bottleneck. For decades, traditional off-the-shelf Ethernet has been the undisputed king of enterprise and cloud networking. It is cheap, standardized…

Source

AI agents have expanded inference from single-turn interactions into multi-step workflows that reason, invoke tools, coordinate subagents, and carry growing...

AI agents have expanded inference from single-turn interactions into multi-step workflows that reason, invoke tools, coordinate subagents, and carry growing context from one turn to the next. The scale of this shift is now visible in raw consumption: across 100 trillion tokens of real-world usage, OpenRouter’s State of AI report found that average prompt tokens per request grew roughly fourfold…

Source

Traditional cloud infrastructure was designed for predictable, general-purpose workloads and standard interfaces. Agentic AI factories connect diverse users,...

Traditional cloud infrastructure was designed for predictable, general-purpose workloads and standard interfaces. Agentic AI factories connect diverse users, agents, applications, data sources, and storage systems to massively accelerated compute at multi-terabit bandwidth per server, making dedicated DPU processing essential for line-rate networking, storage, and security.

Source

AI factories are interconnected systems where fleet economics depend on how efficiently the entire stack converts power and capital into completed agent tasks....

AI factories are interconnected systems where fleet economics depend on how efficiently the entire stack converts power and capital into completed agent tasks. While GPUs run the models, CPUs handle orchestration, tool execution, and sandboxed computation. Unlike conventional computing with stable runtime profiles, agentic workloads are unpredictable and highly variable. Based on telemetry from…

Source

NVIDIA Groq 3 LPX is the interactive AI inference accelerator for the NVIDIA Vera Rubin platform. At the core of the platform is NVIDIA Vera Rubin NVL72, the...

NVIDIA Groq 3 LPX is the interactive AI inference accelerator for the NVIDIA Vera Rubin platform. At the core of the platform is NVIDIA Vera Rubin NVL72, the most versatile machine ever built, delivering high throughput and interactivity across the widest range of AI workloads—from small to large models, both open and closed. Groq 3 LPX, when paired with Vera Rubin NVL72, extends the platform’s…

Source

AI factories are power-constrained industrial systems. The question is no longer how many GPUs fit in a data center, but how much AI output each available...

AI factories are power-constrained industrial systems. The question is no longer how many GPUs fit in a data center, but how much AI output each available megawatt can deliver. For AI inference workloads, this makes application-level performance per watt the key metric for measuring AI factory efficiency. Not every megawatt translates to revenue-generating compute. Power distribution, cooling…

Source

Recommender systems (RecSys) are one of the most ubiquitous machine learning problems in the consumer internet industry yet notoriously difficult to train and...

Recommender systems (RecSys) are one of the most ubiquitous machine learning problems in the consumer internet industry yet notoriously difficult to train and serve at scale. The advent of LLMs has inspired a shift from the traditional embedding-similarity-based objective to a generative one, where the goal is to predict the next action or item in a large catalog given a sequence of user histories.

Source

Uniform Manifold Approximation and Projection (UMAP) is a dimensionality reduction technique widely used for visualization and feature extraction. Applications...

Uniform Manifold Approximation and Projection (UMAP) is a dimensionality reduction technique widely used for visualization and feature extraction. Applications range across exploratory data analysis, topic modeling, and single-cell analysis. Many of these workflows are iterative and exploratory, requiring UMAP to be run repeatedly as users analyze their data or tune parameters. As datasets grow…

Source

AI infrastructure spans multiple layers, from compute and networking to storage, orchestration, and applications. When performance degrades, identifying the...

AI infrastructure spans multiple layers, from compute and networking to storage, orchestration, and applications. When performance degrades, identifying the source can be difficult because a symptom observed at one layer may originate elsewhere in the stack. A full-stack observability strategy connects telemetry across these layers, helping infrastructure and operations teams detect problems…

Source

Meta returns to the open source ecosystem with the release of Muse Glimmer, a 30B open-weight dense model with a 120K+ context window built for local AI...

Meta returns to the open source ecosystem with the release of Muse Glimmer, a 30B open-weight dense model with a 120K+ context window built for local AI agentic work. Optimized to run across a range of NVIDIA edge, desktop, and workstation AI platforms, Muse Glimmer delivers 20K tokens/sec on a single GPU, enabling always-on agents to process data locally and execute complex…

Source

Storage is an active part of every agentic AI workflow. As agents retrieve enterprise knowledge, access persistent memory, reuse key-value (KV) cache data,...

Storage is an active part of every agentic AI workflow. As agents retrieve enterprise knowledge, access persistent memory, reuse key-value (KV) cache data, execute tools, and generate new results, storage systems must continuously supply and preserve the data that moves the agent reasoning loop. Each agent step can trigger multiple storage operations, and those operations can repeat across…

Source

Running a dedicated Kubernetes cluster per team often results in more isolation than an organization requires. While one cluster can be successfully shared...

Running a dedicated Kubernetes cluster per team often results in more isolation than an organization requires. While one cluster can be successfully shared across many teams, the coordination costs increase as the number of teams grows. Challenges include conflicting CRD versions, overlapping RBAC, and no clean way to carve GPU capacity into team-level budgets. At a certain scale…

Source

As agentic and long-context workloads become common, the context lengths increase and attention consumes a larger share of inference time (Figure 1). Because...

As agentic and long-context workloads become common, the context lengths increase and attention consumes a larger share of inference time (Figure 1). Because attention now dominates that cost, how it is designed—not just how it is implemented—increasingly determines a model’s inference performance. Shaping model architecture around how GPUs execute it is the premise of AI model co-design.

Source

Two AI computing clusters built from identical NVIDIA H100, GB200 NVL72, or GB300 NVL72 systems can deliver materially different training throughput. We...

Two AI computing clusters built from identical NVIDIA H100, GB200 NVL72, or GB300 NVL72 systems can deliver materially different training throughput. We routinely see 8% to 12% gaps between partner deployments and the corresponding NVIDIA reference architecture (RA) on the same workload, same model, same global batch size. The cause is often a stack of configuration choices in the kernel…

Source